Education

Ph.D 2011 Quaid-i-Azam University, Islamabad Pakistan


Research Interests


  1. Drug development through enzyme based and cell based assay
  2. Natural Products synthesis including Isocoumarines, Dihydroisocoumarines and their bioevaluation
  3. Prodrug synthesis and bioevaluation
  4. Synthesis and Characterization of alkoxy ester/amide based Liquid Crystalline Materials.


Awards

  1. Awarded the prestigious Brain Korea 21 plus (BK-21 Plus) Post-Doctoral Fellowship South Korea, June 09, 2014 to Feb 29, 2016 at Kongju National University, 182-shinkwan-dong kongju city, chungnam 314-701, South Korea. Supervisor: Prof. Dr. Sung Yum Seo.
  2. Awarded University Grant Commission (UGC) Islamabad research fellowship during M.Phil.studies at Quaid-i-Azam University Islamabad (2001-2002).
  3. Awarded Higher Education Commission (HEC)Islamabad research fellowship during Ph.D.study at Quaid-i-Azam University(2004-2005)
  4. Awarded Research Productive Award 2011-2012
  5. Best performance award for teachers on EVE of word teachers day-2012
  6. Appreciation award from national science fair 2011-2012 organized by intel & ministry of science and technology
  7. Won special 1st prize in science innovations model competition organized by national museum of science, Lahore on November, 14-18, 2012.


Selected Publications


1. Zaman Ashraf, Alamgeer, Munazza Kanwal, Mubashir Hassan, Sahar Abdullah, Mamuna Waheed, Haseeb Ahsan, Song Ja Kim. Flurbiprofen-antioxidant mutual prodrugs as safer NSAIDs; synthesis, pharmacological investigation and computational molecular modeling. Drug Design, Development and Therapy 2016:10 2401–2419.

2. Zaman Ashraf. Metal-catalyzed synthesis of isocoumarin derivatives. Chemistry of Heterocyclic Compounds, 2016, 25(3), 149-151.

3. 3. Anser Ali, Zaman Ashraf, Muhammad Rafiq, Naresh Kumar, Ji hoon Park, Farukh Jabeen, Ki Hong Choi, SeungHyun Lee, Sung-Yum Seo, Eun Ha Choi and Pankaj Attri. Influence of the plasma activated compounds on the melanogenesis and tyrosinase activity. Scientific Report. (2016), 6, 21779, DOI: 10.1038 / srep21779.

4. Aamer Saeed, Shamsul Mahmood, Muhammad Rafiq, Zaman Ashraf, Farukh Jabeen, Sung-Yum Seo, Iminothiazoline-sulfonamide hybrids as Jack Bean Urease inhibitors; Synthesis, kinetic mechanism and computational molecular modeling. Chemical Biology and Drug design, (2016), 87, 434-443.

5. Zaman Ashraf, Abdul Bais, Md. Maniruzzaman Manir, Umar Niazi. Novel Penicillin Analogues as Potential Antimicrobial Agents; Design, Synthesis and Docking Studies. PLoS One (2015), 10(8): e0135293. doi:10.1371/journal. pone.0135293.

6. Zaman Ashraf, Muhammad Rafiq, Sung-Yum Seo, Mustafeez Mujtaba Babar, Najam-us-Sahar Sadaf Zaidi, Synthesis, kinetic mechanism and docking studies of vanillin derivatives as inhibitors of mushroom tyrosinase. Bioorganic & Medicinal Chemistry. 23 (2015) 5870-5880.

7. Zaman Ashraf, Muhammad Rafiq, Sung-Yum Seo, Kang Sung Kwon, Mustafeez Mujtaba Babar, Najam-us-Sahar Sadaf Zaidi, Kinetic and in silico studies of novel hydroxy-based thymol analogues as inhibitors of mushroom tyrosinase. European Journal of Medicinal Chemistry. 2015, 98, 203-211.

8. Zaman Ashraf, Muhammad Rafique, Sung Yum Seo, Mustafeez Mujtaba Babar, Najam-us-Sahar Sadaf Zaidi. Design, synthesis and bioevaluation of novel umbelliferone analogues as potential mushroom tyrosinase inhibitors. J of Enzyme Inhibition & Medicinal Chemistry. 2015 30(6) 874-883.

9. Zaman Ashraf, Aamer Saeed and Humaira Nadeem. Design, synthesis, and docking studies of some novel isocoumarine analogues as antimicrobial agents. RSC Adv., 2014, 4, 53842-53853.

10. Zaman Ashraf, Muhammad Imran and Shahid Amin; Synthesis, Characterization and Invitro hydrolysis studies of some ester and amides prodrugs of Dexibuprofen, Medicinal Chemistry Research ((2012) 21:3361–3368).


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