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Title of the thesis

“Role of Diet in Renal Stone Formation” A study at Liaqat University of Medicine & Health Sciences, Jamshoro.

Name of Author

Dr. Inamul-Haq

Address

H # 10-G, B/D-1 Unit 11 Latifabad, Hyderabad.

Reg #

98-SHD-0598

Roll #

H-5858211

Student’s Batch #

1st

Research Supervisor

Dr Rafi Ahmed Ghauri

Address

Associate Professor of Medicine, Liaqat University of Medicine & Health Sciences, Jamshoro, Hyderabad.


ABSTRACT

The study was carried out to find out correlation between types of diet and types of renal stone formation; role of quality of water and modified diet in the incidence of renal stone formation.

110 patients including male and female with age group ranging from 25 to 65 years were enrolled (before open renal surgery) for investigations admitted in the surgical ward of University of Medicine & Health Sciences, Jamshoro.190 healthy controls were also selected from relatives without any history of renal stone or renal disease. Pretested Performa was given to inquire about the onset of disease, nature of diet and daily activity. Urine sample for D/R and culture, blood samples and surgically removed stones of patients for chemical analysis were collected, and analyzed in laboratory. Chi square test was used for comparison between 110 cases and 190 controls.

Age, sex, area of residence, drinking water source, activity level, dietary and caloric intake were the characteristics compared between the control and the cases.

It was found that the disease is multifactor. Significantly no relationship was found between the age, sex, and area of residence with the renal stone formation. Little difference of dietary and calorie intake was found between the cases and control. Source of drinking water and type of activity were found to be the main causes of the renal stone formation. Use of filter water was less in cases (41.8%) as compared to controls (60.0%). Similarly, stone formers were having more sedentary life style. Calcium oxalate stones were the commonest of all the stones analyzed.

It is concluded that only diet doesn’t contribute in mostly cases of renal stone formation. However, regulation of diet in meaningful way may definitely reduces the chances of occurrence of renal stone formation. High serum calcium levels, lack of activity, low water intake and infection with E.Coli are the main culprit to the problem of renal stone formation in this study.

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